Cart
sales@molnova.com
GSK-3β inhibitor 11
CAS No. 536731-65-4
GSK-3β inhibitor 11( —— )
Catalog No. M35593 CAS No. 536731-65-4
GSK-3β inhibitor 11 (compound 21) is a potent glycogen synthase kinase-3β (GSK-3β) inhibitor with an IC50 of 10.02 μM, demonstrating potential utility in neurodegenerative disease research .
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 65 | Get Quote |
|
| 10MG | 104 | Get Quote |
|
| 25MG | 210 | Get Quote |
|
| 50MG | 339 | Get Quote |
|
| 100MG | 532 | Get Quote |
|
| 500MG | 1134 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameGSK-3β inhibitor 11
-
NoteResearch use only, not for human use.
-
Brief DescriptionGSK-3β inhibitor 11 (compound 21) is a potent glycogen synthase kinase-3β (GSK-3β) inhibitor with an IC50 of 10.02 μM, demonstrating potential utility in neurodegenerative disease research .
-
DescriptionGSK-3β inhibitor 11 (compound 21) is a glycogen synthase kinase-3β (GSK-3β) inhibitor (IC50=10.02 μM). GSK-3β inhibitor 11 can be used in neurodegenerative disease research.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayPI3K/Akt/mTOR signaling
-
TargetGSK-3
-
RecptorGSK-3
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number536731-65-4
-
Formula Weight393.42
-
Molecular FormulaC20H15N3O4S
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 20.83 mg/mL (52.95 mM; Ultrasonic (<60°C)
-
SMILESCOc1cccc(c1)-c1csc(NC(=O)CN2C(=O)c3ccccc3C2=O)n1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Fu G, et al. Pharmacophore Modeling, Ensemble Docking, Virtual Screening, and Biological Evaluation on Glycogen Synthase Kinase-3β. Mol Inform. 2014 Sep;33(9):610-26.?
molnova catalog
related products
-
9-ING-41
9-ING-41 is a glycogen synthase kinase-3 inhibitor.9-ING-41 (2, 4 μM; 48 hours) decreases neuroblastoma cell viability induces apoptosis[2]. 9-ING-41 (0.1-1 μM) inhibits GSK-3 leading to a decreased expression of the NF-κB target XIAP and significant apoptosis in neuroblastoma cells as shown by PARP cleavage, an apoptosis marker[1]. 9-ING-41 (0.5, 1.0, 1.5, 2.0 μM) inhibits the proliferation rate of all TCL and MCL lines with concentrations as low as 1.0 mM.
-
GSK3β inhibitor II
GSK3β inhibitor II is a GSK3β inhibitor. GSK3β inhibitor II exhibits the research potential of Alzheimer's disease (AD).
-
BRD0705
BRD0705 (BRD-0705) is a potent, paralog-selective GSK3α inhibitor with IC50 of 66 nM.
